Paragangliomas classified according to their origin and location Paragangliomas have their origin in cells derived from the embryological neuroectoderm. There are 4 types of paragangliomas (according to Kleinsasser O. Arch. Klin. Exp. Ohren, Nasen, Kehlkopfheilkunde, 1064; 184: 214-25 and Glenner GG, Grimley PM, Atlas of tumor Pathology 1974; p. 18). 1. Branchiomeric group: In the region of the embryological branchiomeres (jugulotympanic ganglion, carotid body, laryngeal ganglia, subclavian ganglion, aorticopulmonary ganglion). There is a close relationship with blood vessels. 2. Intravagal group: In the region of the parasympathetic nerves (jugular ganglion, nodose ganglion). They have their origin within the perineurium. 3. Aortosympathetic group: In the region of the sympathetic nerves of the aorta. 4. Visceral autonomic group: in the nervous system of the heart, digestive tract, liver hilus, and bladder.