From: Establishing a Cancer Genetics Programme in Asia - the Singapore Experience
 | Percentage |
---|---|
nature of deleterious mutation | |
   frameshift | 59 |
   nonsense | 23 |
   large deletions/rearrangements | 18 |
probability of identifying deleterious BRCA1/2 mutation based on risk profile | |
   cancer patient with family history of breast and ovarian cancer (n = 13) | 54 |
   cancer patient with family history of breast cancer (n = 12) | 50 |
   young onset breast cancer without family history of cancer (n = 25) | 16 |
   male breast cancer/bilateral breast cancer (n = 3) | 0 |