Establishing a Cancer Genetics Programme in Asia - the Singapore Experience

Table 4 Genetic testing in Cancer Genetics Programme, National University Hospital, Singapore

patients who underwent genetic testing (n = 127)
test category	%
BRCA1/2 comprehensive sequencing	42
MLH1/MSH2 sequencing	52
APC protein truncation test	2
others^a	4
patients with germline deleterious mutation identified (n = 29)	%
BRCA1/2 mutation	59
MLH1/MSH2 mutation	31
APC mutation	3
others^b	7

^aothers: comprehensive sequencing and rearrangement analysis for von Hippel Lindau (2), karyotyping for Turner's syndrome (1), sequencing for E-cadherin gene mutation (1), sequencing for SDHD gene mutation (1); ^bothers: Turner's syndrome (1), SDHD deleterious mutation (1)

ISSN: 1897-4287