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Table 1 Clinical expression of the variants of hereditary MTC associated syndromes

From: An Introduction to Managing Medullary Thyroid Cancer

  FMTC MEN 2A MEN 2B
medullary thyroid cancer 100% 100% 100%
C-cell hyperplasia 100% 100% 100%
Pheochromocytoma 0% 10% to 60% 50%
Hyperparathyroidism 0% 10% to 25% 0%
Marfanoid habitus 0% 0% 100%
Intestinal ganglioneuromatosis 0% 0% 60% to 90%
Mucosal neuromas 0% 0% 70% to 100%
thick corneal nerves 0% Rare 60% to 90%
  1. FMTC, familial medullary thyroid cancer; MEN 2A/2B, multiple endocrine neoplasia type 2A/2B