Table 3 Allele frequency distribution of the COMT V158M polymorphism in the Australian HNPCC MMR mutation negative patients
Group | Val/Val (%) | Val/Met (%) | Met/Met (%) | n | Pearson's Chi-squared |
|---|---|---|---|---|---|
subject group | 45 (26.9) | 78 (46.7) | 44 (26.4) | 167 | Â |
endometrial/ovarian cancer | 3 (14.3) | 16 (76.2) | 2 (9.5) | 21 | p = 0.002 |
affected with CRC and unaffected with endometrial/ovarian cancer* | 35 (30.4) | 41 (35.7) | 39 (33.9) | 115 | Â |