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Table 1 Genes frequently found methylated in bowel, endometrial, urothelial and breast tumours

From: Epimutations, Inheritance and Causes of Aberrant DNA Methylation in Cancer

Tumour location

Genes methylated

Reference

bowel

MLH1

[11, 12]

 

p14

[11, 12]

 

p16

[11, 12]

 

APC

[11, 12]

 

MGMT

[12]

 

RASSF1A

[12]

 

CDH1

[12]

endometrial

p16

[13]

 

MLH1

 

urothelial

p14

[14]

 

p16

 
 

E-Cadherin (CDH1)

 
 

GSTP1

 

breast

BRCA1

[15]

 

COX2

[16]

 

E-Cadherin (CDH1)

[17]

 

HIC1

[18]