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Table 1 Genes with brain-related function or expression that were significantly altered in association with neurological symptoms in XP

From: Gene Expression Profiling of Xeroderma Pigmentosum

Acc. No. Name Function P value
AA464744 KIAA1111 brain cDNA clone 0.00004
R79082 protein tyrosine phosphatase cellular signalling pathways 0.0004
N35888 phosphomannomutase 2 (PMM2) brain specific glycosylation factor 0.0007
R93912 glycogen synthase kinase 3 beta (GSK3 beta) signal cascade of neuronal apoptosis 0.0008
N70841 GABA-B Receptor 1a neurotransmitter receptor 0.0008
T64482 esterase D/formylglutathione hydrolase expressed predominantly in brain 0.0008
AA463251 nucleosome assembly protein (NAP) induces neuronal apoptosis 0.0008
AA495858 hydroxymethylbilane synthase cell cycle and differentiation in glioma cells 0.0023
AA460927 translin dendritic RNA binding comlex 0.0034
N33331 peroxisome proliferator activated receptor (PPAR) anti-inflammatory and decreases free radical formation 0.0062
AA456830 diacylglycerol kinase (DAGK) myelination 0.0064
AA504333 endothelial-monocyte activating polypeptide II (EMAPII) brain inflammatory response 0.0069
AA644088 cathepsin C upregulated after brain ischaemia 0.0071
H19522 exostoses-like protein 1 (EXTL1) tumour suppressor, highly expressed in brain 0.0076
  transducer of erbB2 (Tob) tumour suppressor, highly expressed in brain 0.0076
AA489331 adenosine deaminase metabolism of adenosine 0.0083