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Figure 3 | Hereditary Cancer in Clinical Practice

Figure 3

From: Gene Expression Profiling of Xeroderma Pigmentosum

Figure 3

Cluster analysis of control and XP complementation groups after UV light treatment. A comparison of control and XP complementation group with gene expression. Control and XP fibroblasts cell line cultures were exposed to UV light. Each column represents gene expression for each of the cell lines after UV light exposure. Down-regulation is represented as green, up-regulation as red and normal expression as yellow. The dendrogram on top represents the relationship between and within the 7 cell lines. The dendrogram on the side represents relatedness of genes based on expression levels. The relatedness of the control fibroblasts and XP complementation groups with the exception of XPD correlated directly with the expected percentage of NER activity present in each cell line

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Hereditary Cancer in Clinical Practice

ISSN: 1897-4287