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Table 3 Prevalence of CHEK2 I157T mutation in colorectal cancer cases according to age at onset

From: Pilot Study on Low Penetrance Breast and Colorectal Cancer Predisposition Markers in Latvia

Age groups

Prevalence of CHEK2 I157T

<51

15% (3/20)

51-60

5.4% (2/37)

61-70

8.9% (7/79)

>70

12.1% (12/99)

total

10.2% (24/235)*

  1. * - significant difference compared to controls (6.4% (63/978); OR = 1.7, p < 0.05)
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Hereditary Cancer in Clinical Practice

ISSN: 1897-4287