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Figure 2 | Hereditary Cancer in Clinical Practice

Figure 2

From: Gene Expression Profiling in Hereditary, BRCA1-linked Breast Cancer: Preliminary Report

Figure 2

Hierarchical clustering of samples, based on 100 genes differentiating between hereditary and sporadic breast tumors. Colors on the right bar code for: regulation of transcription (orange), cell signalling (blue), cell proliferation and death (black), DNA and RNA replication transcription and processing (red), cellular metabolism (yellow), protein synthesis and degradation (green), immune response (violet) and other (grey). It may be seen, that most prominent cluster of genes upregulated in hereditary tumors consists of genes engaged to immune response, what probably reflects lymphocyte infiltrate of those tumors.

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