From: Clinical, Molecular and Geographical Features of Hereditary Breast/Ovarian Cancer in Latvia
HBC suspected (susp.) 1 | HBC susp. 2 | HBC |
---|---|---|
HBOC susp. 1 | HBOC susp. 2 | HBOC |
One-case families | Two-case families | Three-case families |
- at least one of the following criteria has to be met: | - one of the following criteria has to be met: | |
a) breast cancer diagnosed under the age of 40 | a) two breast or two ovarian cancers among first degree relatives (or second through male) at any age | At least three breast or ovarian cancer patients on the same side of family diagnosed at any age; one of those patients is first degree relative (or second through male relative to other two) |
b) medullary or atypical medullary breast cancer | ||
c) male breast cancer | ||
d) breast and ovarian cancer in the same individual at any age | b) one breast cancer diagnosed under the age of 50 and one ovarian cancer diagnosed at any age among first degree relatives (or second through male relatives) | |
e) bilateral breast cancer, one of them diagnosed under the age of 50 |