Table 1 Association of the NOD2 3020insC mutation and selected types of cancer
From: The 3020insC Allele of NOD2 Predisposes to Cancers of Multiple Organs
Site | Number tested | Number positive | Prevalence of 3020insC (%) | Odds ratio | p-value |
|---|---|---|---|---|---|
bladder | 172 | 18 | 10.5 | 1.5 | 0.13 |
breast | 462 | 37 | 8.0 | 1.1 | 0.62 |
with DCIS | 126 | 18 | 14.3 | 2.1 | 0.009 |
without DCIS | 336 | 19 | 5.7 | 0.76 | 0.30 |
colon | 255 | 31 | 12.2 | 1.8 | 0.01 |
kidney | 245 | 8 | 3.2 | 0.4 | 0.02 |
larynx | 223 | 23 | 10.3 | 1.5 | 0.11 |
lung | 258 | 30 | 11.6 | 1.7 | 0.03 |
melanoma | 198 | 10 | 5.1 | 0.7 | 0.31 |
ovary | 317 | 35 | 11.0 | 1.6 | 0.03 |
pancreas | 127 | 6 | 4.7 | 0.6 | 0.37 |
prostate | 298 | 17 | 5.7 | 0.76 | 0.40 |
stomach | 213 | 20 | 9.4 | 1.3 | 0.27 |
thyroid | 82 | 8 | 9.8 | 1.4 | 0.39 |
controls 1910 | 140 | 7.3 |