Table 2 Comparison of grade by mutation (BRCA1 and BRCA2)
Mutation | Grade | Controls (no bilateral oophorectomy) (27 sets, 138 subjects) | Cases (had bilateral oophorectomy) (N = 27) | P |
|---|---|---|---|---|
BRCA1 and BRCA2 | 1 | 2 (2%) | 2 (10.5%) | |
2 | 28 (28%) | 7 (36.8%) | 0.10** | |
3 | 70 (70%) | 10 (53.6%) | ||
missing | 38 | 8 | ||
BRCA1 | 1 | 2 (2.2%) | 1 (6.7%) | |
2 | 26 (28.3%) | 4 (26.7%) | 0.62 | |
3 | 64 (69.5%) | 10 (66.6%) | ||
BRCA2 | 1 | 0 (0%) | 1 (25.0%) | |
2 | 2 (25.0%) | 3 (75.0%) | 0.04 | |
3 | 6 (75.0%) | 0 (0%) |