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Table 3 SIR for offspring CRC depending on the CRC in probands

From: The Swedish Family-Cancer Database: Update, Application to Colorectal Cancer and Clinical Relevance

Familial cancer site Parent only Sibling only Parent and Sibling
  O1) E SIR 95%CI O1) E SIR 95%CI O E SIR 95%CI
Colon 448 239.40 1.87 1.70 2.05 68 21.70 3.13 2.43 3.97 13 1.50 8.73 4.63 14.97
Rectum 227 141.30 1.61 1.40 1.83 30 14.10 2.13 1.44 3.04 1 0.40 2.24 0.00 12.81
Colorectum 664 376.30 1.76 1.63 1.90 93 34.30 2.71 2.19 3.32 17 3.30 5.08 2.95 8.16
  1. Bold type, 95% CI does not include 1.00.
  2. 1)Some observed numbers do not add up because in addition to the right- and left-sided colon cancer, multiple and unspecified colon tumours were included.