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Table 1 Families with multiple occurrence of chordoma

From: Update on the Cytogenetics and Molecular Genetics of Chordoma

Reference

Affected

Chordoma Site

Onset

Foot et al, 1957

brother and sister

sacrococcygeal

middle-age

Enim et al, 1963

two brothers

nasopharyngeal

youth

Kerr et al, 1975

3 in three generations

nasopharyngeal

not specified

Chetty et al, 1991

1 with family history

clival

3 years

Korczak et al, 1997

9 in three generations

clival, spinal

not specified

Stepanek et al, 1998

4 in 2 generations

sacral, clival nasopharyngeal

20, 39, 28, 31

Dalprà et al, 1999

Miozzo et al, 2000

father and two daughters*

clival

before 20

Kelley et al, 2001

two first cousins once removed°

clival

not specified

  1. *third with astrocytoma
  2. °one index case's daughter with pilocystic astrocytoma