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Table 1 The variable expression of MEN1. Percentages of MEN1 germline mutation carriers that develop a MEN1-associated tumour. ACTH: adrenocorticotrophic hormone

From: Diagnosis and Management of Multiple Endocrine Neoplasia Type 1 (MEN1)

Parathyroid adenomas 75-95%
Pancreatic islet cell tumours 70%
   Gastrinomas 45%
   Insulinomas 10%
   Non-functioning (including pancreatic polypeptide producing tumours) 10%
   Other 2%
Pituitary adenomas 47%
   Prolactinomas 30%
   Non-functioning (i.e. not producing hormone) 10%
   ACTH producing 1%
   GH producing 3-6%
Adrenal adenomas 20%
Carcinoid tumours 18%
   Thymus 8%
   Bronchial 8%
   Stomach 5%
Skin lesions 80%
   Angiofibromas 75%
   Collagenomas 5%
Lipomas 30%
Leiomyomas 5%