Table 1 Cumulative risk of breast cancer in Sweden, penetrance of BRCA1 and BRCA2 mutations based on the literature and life expectancy of Swedish women*
Cumulative risk of breast cancer (%) | % alive | |||
|---|---|---|---|---|
by age | all women | BRCA1 mutation carriers | BRCA2 mutation carriers | |
25 | 0.003 | 0.10 | 0.10 | 99.1 |
30 | 0.02 | 0.65 | 0.70 | 98.8 |
35 | 0.09 | 4.26 | 2.47 | 98.4 |
40 | 0.31 | 11.57 | 6.20 | 97.7 |
45 | 0.85 | 23.59 | 10.37 | 96.5 |
50 | 1.74 | 38.31 | 16.18 | 94.3 |
55 | 2.95 | 45.96 | 23.05 | 90.5 |
60 | 4.26 | 53.51 | 30.55 | 85.9 |
65 | 5.59 | 59.38 | 38.61 | 80.5 |
69 | 6.48 | 62.73 | 42.25 | 77.3 |