Table 2 Clinical, pathological and molecular parameters of breast tumours in 13964 G>C carriers
From: Intronic TP53 Germline Sequence Variants Modify the Risk in German Breast/Ovarian Cancer Families
Patients | Age at diagnosis of breast cancer | Histologya | UICCbstage, grade of malignancy | % of TP53 positively stained cell nucleicTumour tissue/Normal tissue |
|---|---|---|---|---|
Sporadic | Â | Â | Â | Â |
   R670 | 63 | IDC | IIIA, G3 | 100/0 |
   R688 | 68 | IDC | I, G3 | 0/0 |
   R728 | 59 | IDC | I, G3 | 0/0 |
   R729 | 50 | IDC | IIA, G3 | 0/0 |
Familial | Â | Â | Â | Â |
   26/III: 1 | 34 | IDC | I, G2 | not available |
   26/III: 2 | 36 | IDC | IIB, G3 | 0/0 |
   P328/II: 5 | 67 | IDC | I, G3 | 0/0 |
   P328/III: 5 | 51 | IDC+ILC | IIB, G2 | 0/0 |