Skip to main content

Advertisement

Table 6 Missense changes identified in exon 15 of the APC gene

From: Germline Missense Changes in the APC Gene and Their Relationship to Disease

Exon Nucleotide Codon Reported in Human Genome Database Number of observations New
15.5 3386 T>C L1129S No 2 Yes
15.7 3949 G>C E1317Q Yes 2 No
15.8 4237 A>G* M1413V No 1 Yes
15.10 4918 C>T R1640W Yes 1 No
15.12 5465 A>T* D1822V Yes 23 No
15.19 7406 C>T* S2469F No 2 Yes
15.19 7504 G>A* G2502S No 3 Yes
15.20 7862 C>G S2621C Yes 2 No
15.21 8068 G>A A2696T No 1 Yes
  1. *Causative mutation identified in patients harbouring these missense changes