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Table 5 Haplotype frequencies

From: Germline Missense Changes in the APC Gene and Their Relationship to Disease

Locus

Number

Percentage

1.1.1.1

164

73.21*

1.1.1.2

1

0.45

1.1.2.1

5

2.23

1.1.2.2

0

0

1.2.1.1

9

4.02

1.2.1.2

1

0.45

1.2.2.1

3

1.34

1.2.2.2

1

0.45

2.1.1.1

3

1.34

2.1.1.2

0

0

2.1.2.1

2

0.89

2.1.2.2

0

0

2.2.1.1

18

8.04*

2.2.1.2

2

0.89

2.2.2.1

12

5.36*

2.2.2.2

3

1.34

Total

224

100.00

  1. Locus position 1, 2, 3, 4 correspond to 5034, 5880, 5465, and 4479 respectively. Each locus has two alleles: 1 = wild type and 2 = mutant type