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Table 3 Frequency of missense changes identified and their association with one another in the APC gene

From: Germline Missense Changes in the APC Gene and Their Relationship to Disease

  Number of times identified
Codon/Codon 545 1493 1499 1678 1756 1822 1960
545 13* 3 1 12 11 3 12
1493   9 0 5 5 4 7
1499    2 2 1 1 2
1678     40 17 18 35
1756      21 6 17
1822       23 20
1960        48
  1. *number of times observed in the study population