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- Open Access
Pericardial metastases from BRCA1-associated peritoneal cancer. Case report
Hereditary Cancer in Clinical Practice volume 13, Article number: A17 (2015)
Women with BRCA1 gene mutations have about 30 to 40 times higher risk of ovarian cancer compared to the population risk (the lifetime risk of BRCA1-dependent ovarian cancer is about 40 percent). Because of the high risk BRCA1 mutations carriers at the age of about 40 are recommended prophylactic salpingo-oophorectomy (after completion of reproductive plans). After the surgery there is still a risk of peritoneal cancer which histologically resembles ovarian cancer, but it is much lower than the risk of ovarian cancer before salpingo-oophorectomy: the cumulative risk of developing cancer of the peritoneum is about 4 percent during 20 years from the removal of ovaries and fallopian tubes.
We are going to present a case of long lasting diagnosis of pericardial metastases from BRCA1-associated peritoneal cancer.
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Abramowska, A., Godlewski, D. Pericardial metastases from BRCA1-associated peritoneal cancer. Case report. Hered Cancer Clin Pract 13, A17 (2015). https://doi.org/10.1186/1897-4287-13-S1-A17
- Public Health
- High Risk
- Ovarian Cancer
- Cancer Research
- Gene Mutation