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Table 2 Bivariate predictors of satisfaction and quality of life

From: Long-term satisfaction and quality of life following risk reducing surgery in BRCA1/2 mutation carriers

Variable

High satisfaction with management decisions

High satisfaction with genetic testing

Quality of life (FACT-B)

 

Percent (N)

Percent (N) SD

Mean (N) SD

Affected status

   

 Unaffected

62% (29)

57% (27)

N/A

 Prev. cancer diagnosis

67% (65)

70% (66)

116.98 (96) 18.99

Oophorectomy

   

 Ovaries intact

53% (18)*

58% (19)

123.64 (17) 2.83

 Risk Reducing Oophorectomy (RRO)

74% (91)

72% (64)

117.67 (64) 2.28

Mastectomy

   

 ≥1 at risk breast

55% (36)*

55% (35)**

119.46 (35) 15.11

 Risk Reducing Mastectomy (RRM)

77% (49)

84% (52)

118.99 (48) 17.22

Timing of RRM

   

 Pre-testing

88% (21) 1.50*

88% (21)**

124.28 (22) 11.04*a

 Post-testing

70% (28) 2.77

82% (31)

114.52 (26) 20.24

 Never

55% (36) 2.89

55% (35)

114.98 (48) 20.57

Timing of RRO

   

 Pre

85% (21) 0.88*

69% (18)

116.37 (17) 22.11

 Post

69% (45) 2.51

73% (46)

118.15 (47) 16.81

 Never

53%(18) 3.47

58% (19)

123.64 (17) 11.68

 Continuous variables

r

r

r

 Age

0.03

−0.06

−0.01

Time since testing

−0.08

−0.05

0.01

 Time since diagnosis

−0.16

−0.260*

<0.01

Time since mastectomy

0.24^

0.11

0.322*

 1st degree relatives w/ breast or ovarian cancer

−0.04

−0.05

0.01

 Pretest anxiety

−0.03

0.08

−0.313**

  1. ^p < 0.10 *p < 0.05 **p ≤ 0.001, acompared to women without this prophylactic surgery.