Table 5 Odd rations (OR) and 95% CI for SHMT C1420T,CBS C699T,CBS C1080T,MS A2756G and MTRR A66G polymorphisms with risk of breast cancer

SHMT 1420CC

48(50.0)

32(37.6)

1.0 (Reference)

SHMT 1420CT

39(40.6)

36(42.4)

0.828(0.54 to 1.27)

0.388

SHMT 1420TT

9(9.40)

17(20)

0.422(0.40 to 1.71)

0.021^*

SHMT 1420CT/TT

48(50.0)

53(62.4)

0.527(0.55 to 1.24)

0.036^*

CBS 699CC

38(39.6)

36(42.4)

1.0 (Reference)

CBS 699CT

44(45.8)

37(43.5)

1.10(0.66 to 2.54)

0.69

CBS 699TT

14(14.6)

12(14.1)

1.14(0.38 to 1.83)

0.73

CBS 699CT/TT

58(60.4)

49(57.6)

1.27(0.45 to 1.65)

0.82

CBS 1080CC

47(49.0)

34(40.0)

1.0 (Reference)

CBS 1080CT

36(37.5)

38(44.7)

1.0 (Reference)

0.86

CBS 1080TT

13(13.5)

13(15.3)

1.04(0.42 to 2.27)

0.90

CBS 1080CT/TT

49(51.0)

51(60)

1.15(0.69 to 3.11)

0.85

MS 2756AA

59(61.4)

61(71.8)

1.0 (Reference)

MS 2756AG

35(36.4)

21(24.7)

2.49(0.29 to 0.833)

0.009^**

MS 2756GG

2(2.2)

3(3.5)

1.72(0.13 to 2.11)

0.36

MS 2756AG/GG

37(38.5)

24(28.2)

2.32(0.29 to 0.82)

0.006^**

MTRR 66AA

13(13.5)

9(10.6)

1.0 (Reference)

MTRR 66AG

79(82.3)

75(88.2)

1.17(0.26 to 2.23)

0.51

MTRR 66GG

4(4.17)

1(1.18)

2.61(0.30 to 1.18)

0.03^*

MTRR 66AG/GG

83(86.5)

76(89.4)

1.84(0.25 to 1.66)

0.047^*