Skip to main content

Advertisement

Springer Nature is making Coronavirus research free. View research | View latest news | Sign up for updates

Table 5 Odd rations (OR) and 95% CI for SHMT C1420T,CBS C699T,CBS C1080T,MS A2756G and MTRR A66G polymorphisms with risk of breast cancer

From: Plasma homocysteine levels and genetic polymorphisms in folate metablism are associated with breast cancer risk in chinese women

Genotype Cases n (%) Controls n (%) ORa(95% CIa) p b
SHMT 1420CC 48(50.0) 32(37.6) 1.0 (Reference)  
SHMT 1420CT 39(40.6) 36(42.4) 0.828(0.54 to 1.27) 0.388
SHMT 1420TT 9(9.40) 17(20) 0.422(0.40 to 1.71) 0.021*
SHMT 1420CT/TT 48(50.0) 53(62.4) 0.527(0.55 to 1.24) 0.036*
CBS 699CC 38(39.6) 36(42.4) 1.0 (Reference)  
CBS 699CT 44(45.8) 37(43.5) 1.10(0.66 to 2.54) 0.69
CBS 699TT 14(14.6) 12(14.1) 1.14(0.38 to 1.83) 0.73
CBS 699CT/TT 58(60.4) 49(57.6) 1.27(0.45 to 1.65) 0.82
CBS 1080CC 47(49.0) 34(40.0) 1.0 (Reference)  
CBS 1080CT 36(37.5) 38(44.7) 1.0 (Reference) 0.86
CBS 1080TT 13(13.5) 13(15.3) 1.04(0.42 to 2.27) 0.90
CBS 1080CT/TT 49(51.0) 51(60) 1.15(0.69 to 3.11) 0.85
MS 2756AA 59(61.4) 61(71.8) 1.0 (Reference)  
MS 2756AG 35(36.4) 21(24.7) 2.49(0.29 to 0.833) 0.009**
MS 2756GG 2(2.2) 3(3.5) 1.72(0.13 to 2.11) 0.36
MS 2756AG/GG 37(38.5) 24(28.2) 2.32(0.29 to 0.82) 0.006**
MTRR 66AA 13(13.5) 9(10.6) 1.0 (Reference)  
MTRR 66AG 79(82.3) 75(88.2) 1.17(0.26 to 2.23) 0.51
MTRR 66GG 4(4.17) 1(1.18) 2.61(0.30 to 1.18) 0.03*
MTRR 66AG/GG 83(86.5) 76(89.4) 1.84(0.25 to 1.66) 0.047*
  1. aOR, odd ratio; CI, confidence interval.
  2. aAdjustment for age at enrollment and duration of fasting.
  3. b*different from reference (p < 0.05), **different from reference (p < 0.01).