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Table 4 Genotype frequencies, allele frequencies at SHMT C1420T,CBS C699T,CBS C1080T,MSA2756G,MTRR A66G candidate loci

From: Plasma homocysteine levels and genetic polymorphisms in folate metablism are associated with breast cancer risk in chinese women

Genotype Cases (n = 96) n (%) Controls (n = 85) n (%) Mutation Allelic frequency p a
    Cases (%) Controls (%)  
SHMT C1420T 96(100.0) 85(100.0) 29.7 41.2 0.039*
CC 48(50.0) 32(37.6)    
CT 39(40.6) 36(42.4)    
TT 9(9.4) 17(20)    
CBS C699T 96(100.0) 85(100.0) 37.5 35.9 0.962
CC 38(39.6) 36(42.4)    
CT 44(45.8) 37(43.5)    
TT 14(14.6) 12(14.1)    
CBS C1080T 96(100.0) 85(100.0) 32.3 37.6 0.624
CC 47(49.0) 34(40.0)    
CT 36(37.5) 38(44.7)    
TT 13(13.5) 13(15.3)    
MS A2756G 96(100.0) 85(100.0) 20.3 11.1 0.004**
AA 59(61.4) 69(81.2)    
AG 35(36.4) 13(15.3)    
GG 2(2.2) 3(3.5)    
MTRR A66G 96(100.0) 85(100.0) 45.3 25.9 0.007**
AA 13(13.5) 9(10.6)    
AG 79(82.3) 75(88.2)    
GG 4(0.04) 1(0.12)    
  1. a*Different from reference (p < 0.05), **different from reference (p < 0.01).