Table 4 Genotype frequencies, allele frequencies at SHMT C1420T,CBS C699T,CBS C1080T,MSA2756G,MTRR A66G candidate loci
Genotype | Cases (n = 96) n (%) | Controls (n = 85) n (%) | Mutation Allelic frequency | p a | |
|---|---|---|---|---|---|
| Â | Â | Â | Cases (%) | Controls (%) | Â |
SHMT C1420T | 96(100.0) | 85(100.0) | 29.7 | 41.2 | 0.039* |
CC | 48(50.0) | 32(37.6) | Â | Â | Â |
CT | 39(40.6) | 36(42.4) | Â | Â | Â |
TT | 9(9.4) | 17(20) | Â | Â | Â |
CBS C699T | 96(100.0) | 85(100.0) | 37.5 | 35.9 | 0.962 |
CC | 38(39.6) | 36(42.4) | Â | Â | Â |
CT | 44(45.8) | 37(43.5) | Â | Â | Â |
TT | 14(14.6) | 12(14.1) | Â | Â | Â |
CBS C1080T | 96(100.0) | 85(100.0) | 32.3 | 37.6 | 0.624 |
CC | 47(49.0) | 34(40.0) | Â | Â | Â |
CT | 36(37.5) | 38(44.7) | Â | Â | Â |
TT | 13(13.5) | 13(15.3) | Â | Â | Â |
MS A2756G | 96(100.0) | 85(100.0) | 20.3 | 11.1 | 0.004** |
AA | 59(61.4) | 69(81.2) | Â | Â | Â |
AG | 35(36.4) | 13(15.3) | Â | Â | Â |
GG | 2(2.2) | 3(3.5) | Â | Â | Â |
MTRR A66G | 96(100.0) | 85(100.0) | 45.3 | 25.9 | 0.007** |
AA | 13(13.5) | 9(10.6) | Â | Â | Â |
AG | 79(82.3) | 75(88.2) | Â | Â | Â |
GG | 4(0.04) | 1(0.12) | Â | Â | Â |