TY - JOUR AU - Valente, Allyson L. AU - Rummel, Seth AU - Shriver, Craig D. AU - Ellsworth, Rachel E. PY - 2014 DA - 2014/07/19 TI - Sequence-based detection of mutations in cadherin 1 to determine the prevalence of germline mutations in patients with invasive lobular carcinoma of the breast JO - Hereditary Cancer in Clinical Practice SP - 17 VL - 12 IS - 1 AB - Loss of cadherin 1 (CDH1) expression, which is normally involved in cell adhesion and maintenance of tissue architecture, is a hallmark of invasive lobular carcinoma (ILCA). Because hereditary cancers may require different risk reduction, counseling and treatment options than sporadic cancer, it is critical to determine the prevalence of germline CDH1 mutations in patients with ILCA. SN - 1897-4287 UR - https://doi.org/10.1186/1897-4287-12-17 DO - 10.1186/1897-4287-12-17 ID - Valente2014 ER -