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Figure 1 | Hereditary Cancer in Clinical Practice

Figure 1

From: Expanding the genetic basis of copy number variation in familial breast cancer

Figure 1

CNV results for WWOX duplication in fBC patient. (A) CNV profile from Cyto2.7 M array data defining the region of duplication including the genomic state (where 0 = the normal two copies and +1 = one extra copy; (B) Location of the duplication within the gene and with respect to the CN assays used in validating the variant; and (C) TaqMan CN Validation assay showing the duplication represented by Hs03934141_cn: note the normal two copies of this region identified in the control, confirmation of the aberrant three copies in the fBC patient and the CN range bars associated with the three technical replicates used to validate the CNVs.

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Hereditary Cancer in Clinical Practice

ISSN: 1897-4287