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Figure 1 | Hereditary Cancer in Clinical Practice

Figure 1

From: The Norwegian PMS2 founder mutation c.989-1G > T shows high penetrance of microsatellite instable cancers with normal immunohistochemistry

Figure 1

Endometrial cancers in carriers of PMS2 c.989-1G > T with and without expression of PMS2. IHC analysis of two adenocarcinomas of the endometrium. Immunhistochemical reaction shows expression (left) or no expression (right) of PMS2. Magnification × 20. Lymphocytes in the tumour sample provide positive control. Both tumours displayed MSI.

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