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Figure 1 | Hereditary Cancer in Clinical Practice

Figure 1

From: A risk of breast cancer in women - carriers of constitutional CHEK2 gene mutations, originating from the North - Central Poland

Figure 1

Pedigrees of families A-E, with CHEK2 mutations. Black symbols - persons affected with cancer; white symbols with a black dot inside - healthy mutation carriers. Age of cancer or age of CHEK2 mutation diagnosis in healthy persons is given in brackets. Br - breast cancer; Lu - lung cancer; Li - liver cancer; Pr - prostate cancer; Co - colon cancer. Arrows indicate probands. I157T, IVS2 + 1G > A or 1100delC - mutation carriers; N - analyzed persons who are not carriers of the mutation; n.t. - not tested.

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Hereditary Cancer in Clinical Practice

ISSN: 1897-4287