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Figure 2 | Hereditary Cancer in Clinical Practice

Figure 2

From: Differential expression of PTEN gene correlates with phenotypic heterogeneity in three cases of patients showing clinical manifestations of PTEN hamartoma tumour syndrome

Figure 2

Molecular analysis of c.406 T- > C; p.136Cys- > Arg mutation within family 1. A) Pedigree of family 1. N.A.: not analysed; MUT+: mutation positive subjects; MUT-: mutation negative subjects. The arrow indicates proband 1 (II-3); III-4: affected daughter; III-3: unaffected daughter; III-2: affected nephew; III-1: unaffected nephew. B) dHPLC analysis within family 1. dHPLC chromatogram obtained for PTEN exon 5 PCR amplified fragment within members of family 1.

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Hereditary Cancer in Clinical Practice

ISSN: 1897-4287