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Table 3 Prevalence of the examined mutations/polymorphisms among PsV cases and healthy controls

From: Psoriasis vulgaris and familial cancer risk- a population-based study

Gene (Mutation) Cases Controls p OR
BRCA1 (ex20)
(ex5-300)
2 / 507 0,39% 1) / 510 0,20% 0,5597 2,016
1 / 507 0,20% 0 0,3156 3,024
CHK2 (I157T) 22 (+) / 503 4,37% 28 (+) / 507 5,52% 0,4000 0,7824
CHK2 (IVS2+1G>A) 2 (+) / 503 0,40% 2 (+) / 507 0,39% 0,9937 1,008
NOD2 (3020insC) 43 (+) / 500 8,60% 41 (+) / 510 8,04% 0,7469 1,076
XPD 936 (D312M) CT TT 200 / 491 40,73% 199 / 493 40,37% 0,9064 1,015
127 / 491 25,87% 114 / 493 23,12% 0,3173 1,160
XPD 2253 (K751Q) GT GG 240 / 503 47,71% 240 / 510 47,06% 0,8347 1,027
82 / 503 16,30% 89 / 510 17,45% 0,6255 0,9213
MC1R (R151C) CT TT 33 / 428 7,71% 35 / 501 6,99% 0,6727 1,112
0 / 428 0% 2 / 501 0,40% 0,1907 0,2331
MC1R (V60L) GT TT 50 / 448 11,16% 63 / 510 12,35% 0,5681 0,8914
1 / 448 0,22% 6 / 510 1,18% 0,0839 0,1879
MC1R (R163Q) AG AA 30 / 435 6,90% 37 / 501 7,38% 0,7724 0,9289
1 / 435 0,23% 2 / 501 0,40% 0,6476 0,5749
VDR (M1T) AG AA 240 / 490 48,98% 252 / 508 49,61% 0,8431 0,9752
99 / 490 20,20% 99 / 508 19,49% 0,7768 1,046
CDKN2A (A148T) 26 (+) / 501 5,19% 28 (+) / 511 5,48% 0,8375 0,9442
p53 (P72R) CG CC 192 / 503 38,17% 195 / 512 38,09% 0,9778 1,004
34 / 503 6,76% 33 / 512 6,44% 0,8403 1,052
rs6983267 GT TT 261 / 501 52,10% 234 / 509 45,97% 0,0516 1,278
119 / 501 23,75% 123 / 509 24,17% 0,8779 0,9776
ATM (E198X) 0 (+) / 499 0% 0 (+) / 508 0% - -
MTHFR (A222V) CT TT 223 / 488 45,70% 227 / 499 45,49% 0,9483 1,008
  47 / 488 9,63% 44 / 499 8,82% 0,6587 1,102