From: Psoriasis vulgaris and familial cancer risk- a population-based study
Gene (Mutation) | Cases | Controls | p | OR |
---|---|---|---|---|
BRCA1 (ex20) (ex5-300) | 2 / 507 0,39% | 1) / 510 0,20% | 0,5597 | 2,016 |
1 / 507 0,20% | 0 | 0,3156 | 3,024 | |
CHK2 (I157T) | 22 (+) / 503 4,37% | 28 (+) / 507 5,52% | 0,4000 | 0,7824 |
CHK2 (IVS2+1G>A) | 2 (+) / 503 0,40% | 2 (+) / 507 0,39% | 0,9937 | 1,008 |
NOD2 (3020insC) | 43 (+) / 500 8,60% | 41 (+) / 510 8,04% | 0,7469 | 1,076 |
XPD 936 (D312M) CT TT | 200 / 491 40,73% | 199 / 493 40,37% | 0,9064 | 1,015 |
127 / 491 25,87% | 114 / 493 23,12% | 0,3173 | 1,160 | |
XPD 2253 (K751Q) GT GG | 240 / 503 47,71% | 240 / 510 47,06% | 0,8347 | 1,027 |
82 / 503 16,30% | 89 / 510 17,45% | 0,6255 | 0,9213 | |
MC1R (R151C) CT TT | 33 / 428 7,71% | 35 / 501 6,99% | 0,6727 | 1,112 |
0 / 428 0% | 2 / 501 0,40% | 0,1907 | 0,2331 | |
MC1R (V60L) GT TT | 50 / 448 11,16% | 63 / 510 12,35% | 0,5681 | 0,8914 |
1 / 448 0,22% | 6 / 510 1,18% | 0,0839 | 0,1879 | |
MC1R (R163Q) AG AA | 30 / 435 6,90% | 37 / 501 7,38% | 0,7724 | 0,9289 |
1 / 435 0,23% | 2 / 501 0,40% | 0,6476 | 0,5749 | |
VDR (M1T) AG AA | 240 / 490 48,98% | 252 / 508 49,61% | 0,8431 | 0,9752 |
99 / 490 20,20% | 99 / 508 19,49% | 0,7768 | 1,046 | |
CDKN2A (A148T) | 26 (+) / 501 5,19% | 28 (+) / 511 5,48% | 0,8375 | 0,9442 |
p53 (P72R) CG CC | 192 / 503 38,17% | 195 / 512 38,09% | 0,9778 | 1,004 |
34 / 503 6,76% | 33 / 512 6,44% | 0,8403 | 1,052 | |
rs6983267 GT TT | 261 / 501 52,10% | 234 / 509 45,97% | 0,0516 | 1,278 |
119 / 501 23,75% | 123 / 509 24,17% | 0,8779 | 0,9776 | |
ATM (E198X) | 0 (+) / 499 0% | 0 (+) / 508 0% | - | - |
MTHFR (A222V) CT TT | 223 / 488 45,70% | 227 / 499 45,49% | 0,9483 | 1,008 |
47 / 488 9,63% | 44 / 499 8,82% | 0,6587 | 1,102 |