From: Mutation spectrum in South American Lynch syndrome families
South American Institutions | Total number of patients/families | MMR mutation carriers | % of MMR mutation carriers | Mean age at CRC diagnosis | Mean age at endometrial cancer diagnosis |
---|---|---|---|---|---|
Hospital Italiano (Buenos Aires, Argentina) | 28 | 14 | 50.0 | 44.3 (SD 6.2) | 46.3 (SD 5.5) |
Hospital de las Fuerzas Armadas (Montevideo, Uruguay) | 25 | 7 | 28.0 | 35.1 (SD 7.6) | 41.5 (SD 8.3) |
Clinica Las Condesa (Santiago, Chile) | 50 | 20 | 40.0 | 35.7 (SD 10.7) | 41.1 (SD 8.8) |
Barretos Cancer Hospitala (Barretos, Brazil) | 23 | 15 | 65.2 | 39.4 (SD 13.8) | 49.8 (SD 5.3) |
Colombiac | 13 | 8 | 61.5 | NA | NA |
Southeastern Brazilb | 128 | 35 | 27.3 | 42.3 (SD 11.4) | 48.8 (SD 2.4) |
Total | 267 | 99 | 37.1 |