Family pedigree of ShaRIT participant illustrating relative inclusion criteria. The pedigree of the participant (arrow), who tested positive, does not show a strong family history of HBOC on either the maternal or paternal side. The participant's mother tested negative for the known family mutation, so it was likely inherited from the participant's father. The participant's brother, two sisters (first-degree relatives), and paternal uncles represent first and second-degree relatives eligible for sharing results and family testing (stars). The participant's two daughters are too young to be included in sharing results or family testing analyses, as they are 7 and 5 years old.