Figure 1From: Familial gastric cancer: detection of a hereditary cause helps to understand its etiology Intramucosal signet ring cell carcinoma. a. Typical small intramucosal focus of a signet ring cell carcinoma in a preventive gastrectomy specimen from a CDH1 mutation carrier (H&E, magnification 100x). b. Detail of signet ring cells between normal foveolar glands and a normal background without signs of gastritis. (H&E, magnification 200x).Back to article page