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Table 3 Significant associations of demographic/clinocopathological data and BRAF mutations in thyroid malignancies

From: BRAF mutations in thyroid tumors from an ethnically diverse group

Factors1

Histology

P value

Test2

Age ≥ 45 years vs. tumor size ≥ 4 cm [87]

PTC

0.018

FET

Age ≥ 45 years vs. vessel invasion [113]

PTC

0.004

FET

Age ≥ 45 years vs. distant metastasis [115]

PTC

0.001

FET

LN + vs. tumor size ≥ 4 cm [43]

PTC

0.044

FET

LN + vs. vessel invasion [59]

PTC

0.013

FET

Increasing age vs. BRAFmut [115]

PTC

0.025

MWU

Family history vs. capsular invasion [64]

TC

0.025

FET

  1. 1Number of cases included in analysis in brackets; 2FET, Fisher´s exact test; MWU, Mann–Whitney U test.