From: HNPCC (Lynch Syndrome): Differential Diagnosis, Molecular Genetics and Management - a Review
Site | Screening |
---|---|
Colon | Annual full colonoscopy initiated between ages 20 and 25 |
Endometrium | Annual transvaginal ultrasound and Pelvic examination beginning at age 30; Endometrial aspiration for pathology assessment |
Ovary | Transvaginal ovarian ultrasound and CA-125 analysis (serious limitations due to reduced sensitivity and specificity) |
Stomach | Consider upper endoscopy in natives of Korea or Japan and/or in families with an excess of stomach cancer |
Upper uro-epithelial tract | Urine samples for rbc and cytology in concert with ultrasound |
Other sites | Consider in families with an excess of cancer of a particular extra-colonic site |