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Table 1 Revised criteria for the identification of suspected HNPCC

From: Nuclear Pedigree Criteria of Suspected HNPCC

One colorectal cancer patient with at least one of the following:
Presence of synchronous or metachronous colorectal tumors in the patient, one of which occurred under the age of 40 years.
Endometrial, urinary tract, or small-intestinal cancer in the patient or a first degree relative (one aged <50 years).
At least two first degree relatives (one aged <50 years) with other extra-colonic cancers (stomach, hepatobiliary system, ovary, or brain).