From: Are population level familial risks and germline genetics meeting each other?
Total numbersa | Family history of concordant cancer | |||||
---|---|---|---|---|---|---|
Cancer site | No | % | Median age | No | Familial proportion % | Median age |
Lip | 5772 | 1.1 | 60 | 119 | 2.1 | 61 |
Salivary gland | 1299 | 0.2 | 53 | 3 | 0.2 | 49 |
Pharynx | 3718 | 0.7 | 58 | 45 | 1.2 | 59 |
Esophagus | 3854 | 0.7 | 63 | 73 | 1.9 | 63 |
Stomach | 6980 | 1.3 | 61 | 411 | 5.9 | 62 |
Small intestine | 2442 | 0.5 | 60 | 54 | 2.2 | 62 |
Colorectum | 48,803 | 9.3 | 63 | 7650 | 15.7 | 63 |
Colon | 30,819 | 5.9 | 64 | 3462 | 11.2 | 63 |
Rectum | 17,984 | 3.4 | 62 | 1054 | 5.9 | 63 |
Liver, primary | 4113 | 0.8 | 63 | 86 | 2.1 | 63 |
Pancreas | 9557 | 1.8 | 64 | 465 | 4.9 | 63 |
Lung | 33,121 | 6.3 | 64 | 4291 | 13.0 | 63 |
Breast | 95,756 | 18.2 | 55 | 16,718 | 17.5 | 55 |
Cervix | 10,542 | 2.0 | 40 | 223 | 2.1 | 39 |
Endometrium | 16,012 | 3.0 | 61 | 821 | 5.1 | 60 |
Ovary | 11,554 | 2.2 | 55 | 495 | 4.3 | 53 |
Prostate | 91,696 | 17.5 | 66 | 24,238 | 26.4 | 65 |
Testis | 8272 | 1.6 | 33 | 158 | 1.9 | 33 |
Kidney | 8574 | 1.6 | 60 | 325 | 3.8 | 59 |
Bladder | 18,738 | 3.6 | 64 | 1319 | 7.0 | 64 |
Melanoma | 37,842 | 7.2 | 52 | 2715 | 7.2 | 52 |
Skin | 19,014 | 3.6 | 67 | 1476 | 7.8 | 66 |
Eye | 1607 | 0.3 | 57 | 10 | 0.6 | 58 |
Nervous system | 21,560 | 4.1 | 51 | 790 | 3.7 | 52 |
Thyroid gland, adenocarcinoma | 6044 | 1.2 | 42 | 136 | 2.3 | 41 |
Endocrine glands | 11,713 | 2.2 | 53 | 341 | 2.9 | 50 |
Bone | 1186 | 0.2 | 39 | 9 | 0.8 | 42 |
Connective tissue | 3754 | 0.7 | 52 | 34 | 0.9 | 52 |
Hodgkins disease | 4064 | 0.8 | 32 | 57 | 1.4 | 36 |
Non-Hodgkins lymphoma | 17,197 | 3.3 | 59 | 743 | 4.3 | 60 |
Myeloma | 5618 | 1.1 | 63 | 140 | 2.5 | 63 |
Leukemia | 14,617 | 2.8 | 60 | 643 | 4.4 | 61 |
All above | 525,019 | 100.0 | 60 | 69,104 | 13.2 | 62 |