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Fig. 4 | Hereditary Cancer in Clinical Practice

Fig. 4

From: Two novel sequence variants in MSH2 gene in a patient who underwent cancer genetic counseling for a very early-onset epithelial ovarian cancer

Fig. 4

MSH2, MSH6 and MLH1 immunohistochemistry (IHC) results in the ovary tumor section of patient carrier of c.1706A > T and c.1711G > T variants in MSH2 exon 11. a Absence of MSH2 protein in the tumor cells; b weak presence of MSH6 protein in the tumor cells; c normal IHC for MLH1 protein in the tumor cells. Filled arrow heads point to IHC– tumor cells, open arrows heads point to IHC+ tumor cells. Blue nuclear staining of lymphocytes indicates positive internal control

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Hereditary Cancer in Clinical Practice

ISSN: 1897-4287