From: Colorectal cancer risk in patients with inflammatory bowel disease and Lynch syndrome
Case # | Â | 1 | 2 | 3 | 4 | 5 |
---|---|---|---|---|---|---|
Gender | Â | M | F | F | M | F |
Ethnicity | Â | Caucasian | Jewish | Caucasian | Caucasian | Caucasian |
MMR Mutation | Â | MLH1 | MSH2 | MSH2 | MSH2 | MSH6 |
Age of IBD dx | Â | 27 | 20 | 27 | 32 | 23 |
Site of IBD | Â | Ileum | Pancolitis | Pancolitis | Proctitis | Pancolitis |
Colectomy, age | Â | 21 | 57 | 43 | 44 | 63 |
Cancer/dysplasia | Â | CRC dx 21 | LGC* | None | TVA/HGD** dx 44 | Endometrial dx 57 |
Smoking hx | Â | N | Y | N | Y | N |
IBD medication | 5-ASA | N | Y | Y | Y | Y |
 | Steroids | N | Y | Y | N | Y |
 | Antibiotics | N | Y | Y | Y | N |
Age of CRC in 10 or 20 kin | # of kin | 2 | 3 | 2 | 4 | 5 |
 | Mean age | 40.5 | 30.7 | 35.5 | 49.7 | 78.4 |