Table 8 a, b. Disease severity and its association with the four common polymorphic alleles identified as being in linkage disequilibrium
From: Germline Missense Changes in the APC Gene and Their Relationship to Disease
a. Association between polymorphisms at 5034, 5465, 5880 and disease severity | ||
|---|---|---|
| Â | Moderate/severe | Mild |
At least 1 polymorphic allele | 41 | 20 |
Wild type at all 3 sites | 33 | 26 |
OR = 1.62 (0.70-3.63) | ||
b. Association between polymorphism 4479 and disease severity | ||
| Â | Moderate/severe | Mild |
Polymorphic allele | 3 | 4 |
Wild type | 71 | 42 |
OR = 0.44 (95% CI 0.06-2.78) | ||