From: Clinical and genetic characterization of hereditary breast cancer in a Chinese population
Variable | No (BC) (%)(n = 120) | No (high-risk group) (%)(n = 120) | P-Value |
---|---|---|---|
BRCA1 | 3(2.5) | 0(0.0) | 0.247 |
BRCA2 | 9(7.5) | 2(1.7) | 0.031 |
ATM | 1(0.8) | 3(2.5) | 0.622 |
MUTYH | 2(1.7) | 7(5.8) | 0.171 |
BARD1 | 1(0.8) | 1(0.8) | 1.0 |
BRIP1 | 0(0.0) | 1(0.8) | 1.0 |
CHEK2 | 2(1.7) | 0(0.0) | 0.498 |
NBN | 1(0.8) | 0(0.0) | 1.0 |
PALB2 | 2(1.7) | 0(0.0) | 0.498 |
RAD51C | 1(0.8) | 0(0.0) | 1.0 |
TP53 | 1(0.8) | 0(0.0) | 1.0 |
No causative variants | 97(80.9) | 106(88.4) | 0.157 |